Timolol Eye Drops in the Treatment of Acute Migraine Headache

Stopped early · Not applicable · Has a placebo group

Conditions studied: Migraine

In brief

The goal of this study is to determine whether timolol eye drops are effective in alleviating acute migraine headaches. Subjects will be randomized to receive either timolol eye drops or placebo (tears) to use as a migraine abortive medication.

Key facts

Study ID

NCT02630719

Run by

University of Missouri, Kansas City

People needed

10

Starts

2016-01-01

Expected to finish

2017-08-01

Last updated by the study team

2019-05-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of migraine headache

You may not qualify if…

• Non-migraine headache
• Use of systemic beta-blocker
• Medical history of hypotension, bradycardia, syncope or other significant cardiovascular disease
• Medical history of difficulty breathing, asthma or chronic obstructive pulmonary disease or other pulmonary disease
• Medical history of glaucoma, ocular hypertension or hypotony, punctual stenosis, current use of other ophthalmic medications
• Previous adverse reaction to timolol or other beta-blockers
• Inability to self-administer eye drop due to physical or cognitive disorders
• Currently pregnant or breastfeeding
• Pregnant in the past year
• Non-english speaker

Where it is running

• Truman Medical Center — Kansas City, Missouri, United States

Full record on ClinicalTrials.gov

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