Symptom Control Satisfaction With Proton Pump Inhibitor Regimen

Completed · Phase 4

Conditions studied: Heartburn

In brief

The overall aim of this study is to assess if patients with persistent gastroesophageal reflux disease (GERD) symptoms receiving sub-optimal omeprazole dosing experience improvement in GERD symptoms when prescribed an optimal dosing regimen. The optimal dosing regimen is defined as taking omeprazole 30 minutes prior to the first meal of the day.

Key facts

Study ID

NCT02623816

Run by

MetroHealth Medical Center

People needed

64

Starts

2014-08-01

Expected to finish

2015-12-01

Last updated by the study team

2022-10-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• ≥ 18 years old
• taking omeprazole 20 mg
• episodic heartburn at least 3 times per week
• provides consent and be willing to complete study questionnaires
• read, speak and write English

You may not qualify if…

• weight loss (alarm symptom)
• normal esophagogastroduodenoscopy (EGD) in last one year
• pregnant or women planning on becoming pregnant at any time during the study
• history of Barrett's esophagus
• prior esophageal strictures
• intolerance/allergy to study medications
• patients on plavix or a history of upper gastrointestinal surgery
• investigators or their immediate family (spouse, children, sibling)

Where it is running

• MetroHealth Medical System — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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