The Use of Ambulatory Blood Pressure Monitors to Assess Angiotensin Converting Enzyme Inhibitors

Status unconfirmed · Phase 1

Conditions studied: Hypertension, Resistant to Conventional Therapy

In brief

The purpose of this study is to use ambulatory blood pressure monitors to investigate whether enalapril is superior to lisinopril in managing nocturnal hypertension in patients with resistant hypertension currently treated with daytime angiotensin converting enzyme inhibitors.

Key facts

Study ID

NCT02623036

Run by

Memorial Health University Medical Center

People needed

20

Starts

2015-11-01

Expected to finish

2018-04-01

Last updated by the study team

2017-05-25

Who can join

Age: 18 and older, up to 79. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients with clinic blood pressure > 140/90 mm Hg on 3 antihypertensives or clinic blood pressure < 140/90 mm Hg on 4 antihypertensives
• Currently treated with an angiotensin converting enzyme inhibitor

You may not qualify if…

• Chronic kidney disease (CKD) stage 4 or worse
• Pheochromocytoma
• Unstable cardiovascular disease Stroke, Transient Ischemic Attack, Unstable Angina, or Myocardial infarction in the last 30 days
• Hyperaldosteronism
• Current pregnancy
• Shift worker at night
• Presenting blood pressure > 180/110 mm Hg

Where it is running

• Memorial Family Medicine Center — Savannah, Georgia, United States (enrolling)

Full record on ClinicalTrials.gov

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