Aerobic Exercise for Cognition in Schizophrenia

Completed · Not applicable

Conditions studied: Schizophrenia

In brief

This study will evaluate the ability of aerobic exercise (AE) to improve cognition in people with schizophrenia. Participants will be randomly assigned to one of two interventions: (1) aerobic exercise class (stationary bicycle, or "spin" class) for up to 45 minutes three times per week for 12 weeks, or (2) balance and stretching class for up to 45 minutes three times per week for 12 weeks.

Key facts

Study ID

NCT02621983

Run by

VA Office of Research and Development

People needed

50

Starts

2016-01-01

Expected to finish

2018-07-01

Last updated by the study team

2019-10-23

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of schizophrenia or schizoaffective disorder
• maintained on stable doses of outpatient psychiatric medications for at least 30 days
• compliant with outpatient follow-up
• have a stable place to live
• access to transportation to the hospital
• doing less than 20 minutes per week of regular physical activity in the past month

You may not qualify if…

• Bipolar disorder;
• active substance dependence within the prior 30 days
• more than 2 psychiatric admissions within the prior six months
• known HIV infection or AIDS
• history of traumatic brain injury
• current seizure disorder
• Alzheimer's disease or other dementia
• clinical history of mild cognitive impairment
• Parkinson's disease
• other current clinically significant neurological disease
• unstable medical condition that would be expected to interfere with fitness training
• significant hearing or visual impairment

Where it is running

• Atlanta VA Medical and Rehab Center, Decatur, GA — Decatur, Georgia, United States

Full record on ClinicalTrials.gov

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