De Novo Lipogenesis of Sebaceous Glands in Acne

Completed · Early Phase 1

Conditions studied: Acne Vulgaris

In brief

There are two purposes of this study: 1. First, the investigators want to see what the differences are in de novo sebaceous lipid production of people with and without acne. 2. Secondly, the investigators want to know what happens to sebaceous gland de novo lipid production before and after treatment with topical tretinoin and oral isotretinoin.

Key facts

Study ID

NCT02620813

Run by

University of California, Davis

People needed

32

Starts

2015-10-01

Expected to finish

2017-10-12

Last updated by the study team

2021-08-05

Who can join

Age: 15 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 15 to 45 years of age
• Subject/Parents/Legal Guardian be able to read and comprehend study procedure and consent forms
• Have acne that is diagnosed by a board certified dermatologist
• Meet one of the following criteria:
• already been prescribed oral isotretinoin for treatment of acne
• have already been prescribed a topical retinoid
• eligible for prescription of topical tretinoin

You may not qualify if…

• Those who have already initiated or completed a course of systemic isotretinoin
• Those with seborrheic dermatitis, rosacea, or polycystic ovary syndrome
• Those who are pregnant in female participants
• Those who do not fit the inclusion criteria

Where it is running

• Dermatology Research Area — Davis, California, United States
• UC Davis Department of Dermatology — Sacramento, California, United States

Full record on ClinicalTrials.gov

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