EMS Use of Isopropyl Alcohol Aromatherapy Versus Ondansetron
Completed · Not applicable
Conditions studied: Nausea
In brief
Nausea is a common symptom encountered in the Emergency Medical Services (EMS) environment that is often treated with oral or intravenous anti-emetic medications. Research Design/Plan: This will be a randomized equivalence study comparing the reduction in a patient's reported level of nausea after treatment with either Ondansetron or IPA Methods: Patients who report nausea and/or vomiting in the normal evaluation and care of after calling 911 for Emergency Medical Care will be offered enrollment in the study. A short script will be attached to the outside of each study packet providing information about the study and its risks and benefits. Verbal or written (waiver of informed consent will be requested) permission will be obtained to start randomization. If the patient agrees to enroll then the study packet will be opened and utilized. All Advanced Life Support Ambulances in the San Antonio Fire Department will have sealed numbered opaque boxes or envelopes with either: 70% Isopropyl Alcohol swabs or ondansetron. Six Visual Nausea Severity Scoring cards will be provided with a marking pen to record timed nausea levels before and upon arrival to the Emergency Department and 15 minutes after treatment whichever comes first. Clinical Relevance: This treatment has not been studied in the unique environment encountered by Paramedics in the Pre-Hospital setting. If this treatment is found to be effective, it many offer a very simple, extremely inexpensive and non-invasive (basic life support) approach for the treatment of nausea.
Key facts
- Study ID
- NCT02618343
- Run by
- The University of Texas Health Science Center at San Antonio
- People needed
- 51
- Starts
- 2016-10-04
- Expected to finish
- 2019-03-01
- Last updated by the study team
- 2021-03-24
Who can join
Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults (non-pregnant) age 18 years or older with a symptom of nausea and/or vomiting requiring treatment by EMS
You may not qualify if…
- Children not yet 18 years of Age
- Prisoners or those under arrest
- Patients known or suspected to be Pregnant
- Clinical Intoxication
- Patients unable to provide informed consent
- Recent Upper respiratory Tract infection
- Inability to follow instructions
- Inability to inhale through Nares
Where it is running
- San Antonio Fire Department EMS Division — San Antonio, Texas, United States
Full record on ClinicalTrials.gov
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