Kinematic Analysis: Posterior Stabilized, Fixed Bearing Total Knee Arthroplasty With Attune Knee System - Phase 2
Completed
Conditions studied: Total Knee Arthroplasty, Osteoarthritis
In brief
A better understanding of knee joint kinematics is important to explain the premature polyethylene wear failures within total knee arthroplasties (TKAs) and to help design a prosthesis that most closely approximates the normal knee. Specifically, posterior stabilizing (PS) knees have been found to be associated with lower amounts of posterior femoral rollback, higher occurrence of reverse axial rotation and increased amount of condylar lift-off. The DePuy Synthes Joint Reconstruction's Attune PS fixed bearing (FB) knee system has incorporated subtle changes in its design to address restoration of kinematics that more closely resemble those of a normal knee. To understand if this design is able to effectively restore kinematics in the implanted knee, further in vivo analysis is necessary. This continuation of the study will analyze 30 subjects with the Attune PS FB 3 months post-operatively using the University of Tennessee's mobile fluoroscopy unit while performing three daily activities, level walking, ramp down and deep knee bend.
Key facts
- Study ID
- NCT02613338
- Run by
- The University of Tennessee, Knoxville
- People needed
- 30
- Starts
- 2015-11-01
- Expected to finish
- 2019-01-01
- Last updated by the study team
- 2019-11-12
Who can join
Age: 30 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- At least three (3) months post-operative with no other surgical procedures conducted within the past six months
- Between 30-80 years of age
- Body weight of less than 280 lbs
- Must be between 160cm (5'3) and 193cm (6'4) tall
- Body Mass Index (BMI) >18.5 and <35
- Judged clinically successful with a Knee Society score (KSS) of greater than 80
- Have good-to-excellent post-operative passive flexion with no ligamentous laxity or pain
- Must be able to walk on level ground without aid of any kind, perform a ramp descent, and a deep knee bend (DKB), all without assistance
- Will have a DePuy Attune PS TKA
You may not qualify if…
- Pregnant or potentially pregnant females will be excluded from the study.
Where it is running
- OrthoCarolina Research Institute — Charlotte, North Carolina, United States
- Abercrombie Radiology — Knoxville, Tennessee, United States
- Dougherty Engineering Building, Room M007 — Knoxville, Tennessee, United States
- Perkins Hall, The University of Tennessee — Knoxville, Tennessee, United States
- Science and Engineering Research Facility, The University of Tennessee — Knoxville, Tennessee, United States
Full record on ClinicalTrials.gov
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