Muscle Connective Tissue in Limb Development and Disease
Recruiting now
Conditions studied: Radial Dysplasia
In brief
The objective of this work is to understand how the disruption of the muscle connective tissue contributes to the limb soft-tissue defects in radial dysplasia. In parallel, the researchers will investigate the role of muscle connective tissue in normal limb development.
Key facts
- Study ID
- NCT02611089
- Run by
- King's College London
- People needed
- 150
- Starts
- 2016-02-20
- Expected to finish
- 2036-08-01
- Last updated by the study team
- 2025-08-27
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with a clinical diagnosis of radial dysplasia, requiring reconstructive surgery
- Either sex
- Informed (parental) consent to participate
You may not qualify if…
- Patients with a clinical diagnosis of radial dysplasia, but not requiring reconstructive surgery
- Patients with a diagnosis other than radial dysplasia
- Patients with extensive previous scarring to their forearm and hand.
- Patients with a significant pathological skin or soft tissue lesion at the donor site.
- Controls
- Inclusion Criteria:
- Patients with an injury requiring reconstructive surgery
- Either sex
- Informed (parental) consent to participate
- Exclusion Criteria:
- Patients with extensive previous scarring to their forearm and hand.
- Patients with a significant pathological skin or soft tissue lesion at the donor site.
Where it is running
- Oxford University Hospitals — Oxford, Oxfordshire, United Kingdom (enrolling)
- Royal Free Hospital — London, United Kingdom (enrolling)
- Guy's and St Thomas' Hospital — London, United Kingdom (enrolling)
- Chelsea and Westminster Hospital NHS Foundation Trust — London, United Kingdom (enrolling)
- Great Ormond Street Hospital for Children NHS Foundation Trust — London, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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