Salivary Biomarkers in Pediatric Traumatic Brain Injury

Completed

Conditions studied: Traumatic Brain Injury

In brief

By studying individual biomarkers in body fluids such as saliva, there is a potential for detecting injury to the brain resulting from an acute traumatic even that may not be detectable by conventional neuroimaging like CT scans.

Key facts

Study ID

NCT02609568

Run by

Valleywise Health

People needed

77

Starts

2014-04-16

Expected to finish

2017-03-30

Last updated by the study team

2017-09-14

Who can join

Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children aged 0 to 20 who present to the pediatric ED or trauma bay with an isolated acute head injury (moderate or severe) and are admitted for inpatient management;
• Pediatric patients who present to the ED with non-trauma complaints; and
• Pediatric patients who present to the ED with non-head trauma such as musculoskeletal injuries.

You may not qualify if…

• Patients with multisystem trauma;
• Patients with minor head trauma (GCS 13-15) discharged from the pediatric ED
• Patients with other pre-existing neurological conditions (such as cerebral palsy, chronic seizure disorder, VP shunts);
• Patients with a history suggestive of head trauma from chronic abuse;
• Incarcerated patients or patients from juvenile detention facilities;
• Refusal of parent/patient to participate for any specific reason.

Where it is running

• Maricopa Integrated Health System — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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