Changes in Cerebral Oxygenation During the Administration of Cell Saver Blood and Allogeneic Blood

Completed

Conditions studied: Idiopathic Scoliosis, Transfusion Reaction

In brief

A prospective study designed to evaluate changes in tissue and cerebral oxygenation before and following administration of blood for patients undergoing spinal surgery. Red blood transfusions (autologous and allogeneic) are indicated to improve oxygen delivery to the tissues and hence tissue oxygenation. Despite the presumed efficacy, there are limited data to demonstrate changes in tissue oxygenation with the administration of blood. Furthermore, the administration of both autologous blood from cell saver and allogeneic blood can be associated with both acute and long-term deleterious physiologic effects which may impact the perioperative course. As such, data are needed to clearly delineate the benefits of transfusion during the perioperative period.

Key facts

Study ID
NCT02607150
Run by
Nationwide Children's Hospital
People needed
50
Starts
2014-12-01
Expected to finish
2016-03-01
Last updated by the study team
2016-04-07

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

You may not qualify if…

Where it is running

Full record on ClinicalTrials.gov

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