Mechanisms of Ischemic Stroke in Cancer Patients
Completed
Conditions studied: Stroke, Cancer
In brief
The purpose of this study is to better understand the causes of stroke in people with cancer. Active cancer increases the risk of stroke. The investigators do not know exactly why this occurs but one possible reason is that people with cancer may have thicker blood than people without cancer. Thick blood can sometimes cause blood clots to form in the heart, which can then travel to the brain and cause stroke. This study is being done to help figure out why this and other causes of stroke occur in people with cancer. The investigators expect that information from this study will help doctors to more effectively prevent and treat stroke in individuals with cancer.
Key facts
- Study ID
- NCT02604667
- Run by
- Weill Medical College of Cornell University
- People needed
- 150
- Starts
- 2016-04-08
- Expected to finish
- 2020-09-01
- Last updated by the study team
- 2021-05-05
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 18 years of age or older
- Active solid tumor cancer (for Groups 1 and 3 only)
- MRI confirmed acute ischemic stroke (for Groups 1 and 2 only)
- Available for blood draw at 96 hours (+/- 24 hours) from last known well time (for Groups 1 and 2 only) or within 2 weeks of enrollment (for Group 3)
- Available for TCD within 2 weeks of enrollment
You may not qualify if…
- Primary brain tumor or hematological cancer
- Treatment with intravenous or intraarterial thrombolysis or mechanical embolectomy
- Platelets < 50,000/mm3
- Hemodialysis within 14 days
- Active pregnancy
- Infection within 14 days per Infectious Diseases Society of America (IDSA) criteria
Where it is running
- Memorial Sloan Kettering Cancer Center — New York, New York, United States
- New York-Presbyterian Hospital/Weill Cornell Medical Center — New York, New York, United States
Full record on ClinicalTrials.gov
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