A Prospective Analysis on the Expansion Rates of Abdominal Aortic Aneurysms

Status unconfirmed

Conditions studied: Abdominal Aortic Aneurysm

In brief

Abdominal aortic aneurysm (AAA) disease is an abnormal bulging of the main abdominal artery, which is the called the abdominal aorta. The purpose of this observational study is to identify whether a blood biomarker protein RhoA can predict which small AAA patients may need surgery in the future. Participating patients will receive an ultrasound and blood draw. The patients will be divided into expanding and stable aorta groups after determining each patient's aortic expansion rate. The blood RhoA levels and aortic expansion rates between both groups would then be compared to look for any relationships.

Key facts

Study ID

NCT02604303

Run by

VA Northern California Health Care System

People needed

150

Starts

2015-09-01

Expected to finish

2020-09-01

Last updated by the study team

2019-11-29

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Over the age of 21 years.
• Have been screened for abdominal aortic aneurysm by the VA or found to have an aorta visualized from diagnostic imaging at least once.
• Currently on no medications which would interfere with wound healing or compromise the blood draw.
• Not pregnant nor planning to become pregnant during study period.
• No previous history of AAA repair.

You may not qualify if…

• Failure to meet inclusion criteria.
• Patient withdraws from the study.
• In the opinion of the principle investigator, multiple comorbidities that make analysis difficult.

Where it is running

• Sacramento VA Medical Center — Mather, California, United States

Full record on ClinicalTrials.gov

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