Observational Analysis of T Cell Responses to SPIREs for Multiple Allergens in Subjects With Allergy in North America

Stopped early

Conditions studied: Allergy

In brief

This is a research study intending to look at the response of a specific type of allergy cells in the blood (called T cells) to a a type of immunotherapy product known as SPIREs (Synthetic Peptide Immuno-Regulatory Epitopes), across a broad range of subjects. This is a non-interventional study in which no investigational product will be administered to any subject.

Key facts

Study ID

NCT02601690

Run by

Adiga Life Sciences, Inc.

People needed

199

Starts

2015-10-01

Expected to finish

2017-06-25

Last updated by the study team

2019-04-09

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female, aged 18-65 years.
• Willing and able to provide written informed consent.
• One year history of allergic rhinoconjunctivitis to one or more of cat, short ragweed, Rye grass, or HDM.
• Positive skin prick test to each allergen for which a subject has a qualifying clinical history.

You may not qualify if…

• Clinically relevant history of alcohol or drug abuse.
• Use of any oral or parenteral (except low dose inhaled) corticosteroids within 2 months prior to the visit or any other immunosuppressive therapy within 3 months prior to the visit.
• Vaccination/ inoculation within the 6 weeks prior to the first visit.
• A history of any significant disease or disorder (e.g. autoimmune, cardiovascular, pulmonary, gastrointestinal, liver, renal, neurological, musculoskeletal, endocrine, metabolic, neoplastic/malignant, psychiatric, major physical impairment, severe atopic dermatitis).
• Subjects who have taken an investigational drug within 6 weeks prior to the visit or are currently participating in any other clinical study.
• Recent blood donation of an amount of >100 mL.
• Immunotherapy within the last 5 years to any of the allergens for which a subject would otherwise be eligible on the basis of clinical history and skin prick test result.

Where it is running

• Empire Clinical Research — Upland, California, United States
• O&O Alpan — Fairfax, Virginia, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.