Novel Approaches to Reducing Tobacco Related Harm

Completed · Not applicable

Conditions studied: Smoking, Tobacco Smoking Behavior, Cigarette Smoking

In brief

The purpose of this study is to assess initial reactions to alternative nicotine/tobacco products among smokers living with HIV.

Key facts

Study ID

NCT02600273

Run by

Duke University

People needed

18

Starts

2017-01-01

Expected to finish

2019-06-01

Last updated by the study team

2020-09-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• HIV-infected adults age 18 and older currently receiving HIV care
• Self-report smoking ≥10 cigarettes/day of a brand delivering >0.5mg nicotine for >2yrs
• Have afternoon expired CO concentrations of ≥10ppm or morning urinary cotinine >100ng/ml (as measured with NicAlert)

You may not qualify if…

• Impaired mental status as assessed by observation
• Acute intoxication as measured by breath alcohol level (BAL) > 0
• Current use of nicotine replacement or other pharmacotherapy for smoking cessation
• Previous use of e-cigarettes
• Use of other tobacco products (e.g., chew tobacco, cigars) on > 10 of the past 30 days
• Unstable HIV or associated comorbidities, as determined by a licensed medical professional.
• Pregnancy (Females testing positive for pregnancy and any participants wishing to quit immediately will be referred to community smoking cessation treatment and will be excluded from the study)
• Blood pressure at or above 160/100 or below 90/50
• Heart rate at or above 105 bpm or below 45 bpm

Where it is running

• Duke University School of Medicine — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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