Mitochondrial Dysfunction, Inflammation, and White Matter Integrity in Youth With Mood Disorders

Completed

Conditions studied: Depression, Bipolar Disorder, Bipolar Disorder Not Otherwise Specified, Unspecified Mood Disorder

In brief

This study consists of three separate appointments including a clinical assessment (interview and questionnaires), a blood draw, a social stress test, and a brain MRI.

Key facts

Study ID

NCT02596698

Run by

University of Minnesota

People needed

54

Starts

2015-10-31

Expected to finish

2018-03-31

Last updated by the study team

2020-02-05

Who can join

Age: 13 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• Past history of brain damage, a seizure disorder, increased intracranial pressure, history of head trauma with loss of consciousness for >15 minutes, history of stroke, mental retardation, or other serious neurological disorder
• MRI contraindications such as braces, metal implants, implanted medical devices, or claustrophobia
• Intelligence quotient < 80
• Severe or acute medical illness
• A history of current (past 3 months) substance disorder (defined by DSM-5) with the exception of Nicotine
• Refusal to cooperate with study procedures
• Active suicidal ideation with intent
• Self-injury that requires medical attention (e.g. stitches) or gets significantly worse during the course of the study

Where it is running

• Ambulatory Research Center (ARC) — Minneapolis, Minnesota, United States
• Center for Magnetic Resonance Research — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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