The Effect of Diluted Sodium Hypochlorite Solution and Moisturizers on Skin Barrier Function in Atopic Dermatitis

Completed · Not applicable

Conditions studied: Atopic Dermatitis

In brief

The goal is this study is to investigate the effects of dilute bleach on the skin of subjects with atopic dermatitis and those with healthy skin. The second goal is to evaluate the effects of different moisturizers on the skin barrier of subjects with and without atopic dermatitis. The investigators hypothesize that the bleach bath will increase the skin pH, decrease the skin hydration, and increase skin water loss in all study subjects. Secondly, the investigators hypothesize that moisturizers with the lowest pH and the highest water to oil ratio will result in improved skin barrier function. Furthermore, the investigators believe there will be a greater improvement in patients with atopic dermatitis.

Key facts

Study ID

NCT02594969

Run by

University of California, Davis

People needed

20

Starts

2014-01-01

Expected to finish

2015-05-01

Last updated by the study team

2017-05-30

Who can join

Age: 8 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 8 years to 65 years
• Has been diagnosed with atopic dermatitis by a board-certified dermatologist at UC Davis
• Subject/parents/legal guardians able to read and comprehend the study procedure and consent forms.

You may not qualify if…

• Those who are pregnant, prisoners, or cognitively impaired
• Those who do not fit the inclusion criteria

Where it is running

• UC Davis Department of Dermatology — Sacramento, California, United States

Full record on ClinicalTrials.gov

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