Activity & Cognition After Treatment for Breast Cancer
Completed · Not applicable
Conditions studied: Breast Cancer, Mild Cognitive Impairment, Physical Activity
In brief
This study addresses an important public health concern; impoverished cognitive function associated with treatment of breast cancer. Due to increased awareness of breast cancer combined with advances in medical care, there are over 2.8 million women living with a history of breast cancer in the U.S. alone. Chemotherapy and adjuvant therapy to remove cancerous tissue can result in deficits in attention, speed of processing, memory, and quality of life. Physical activity has been associated with a number of health benefits for breast cancer survivors including improvements in cognitive function. However, most of the literature is cross-sectional and it is unclear whether acute (single) bouts of physical activity affect cognition and, if they do, how long this effect lasts. This study will be the first, to the investigators' knowledge, to examine the effects of an acute bout of aerobic exercise on cognitive functioning in breast cancer survivors. Specifically, the investigators will determine the effects of a 30-minute moderate intensity aerobic exercise session (treadmill walking) on immediate and one hour follow up changes in measures of processing speed, memory, and executive function. Additionally, accelerometer cut-points for physical activity intensities in breast cancer survivors will be assessed. Finally, the investigators will examine the association of cardiorespiratory fitness and physical activity with changes in cognitive function. Findings from this study will allow researchers to determine whether any acute effects of exercise on cognition are retained over time and therefore have real meaning in the context of one's daily life.
Key facts
- Study ID
- NCT02592070
- Run by
- University of Illinois at Urbana-Champaign
- People needed
- 31
- Starts
- 2015-07-01
- Expected to finish
- 2016-04-01
- Last updated by the study team
- 2020-02-10
Who can join
Age: 30 and older, up to 60. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- women between 30 and 60 years of age
- diagnosis of breast cancer
- no longer undergoing treatment
- fluent in English
- no history of dementia or organic brain syndrome
- not currently pregnant
- able to walk unassisted
- no health reasons that would prevent ability to exercise
- not currently enrolled in another exercise research study
- reported trouble with memory/concentration
- physician's consent
You may not qualify if…
- male
- no diagnosis of breast cancer
- outside of 30-60 years of age
- currently undergoing treatment for breast cancer
- inability to communicate in English
- history of dementia or organic brain syndrome
- pregnant
- unable to walk unassisted
- other health reasons that may prevent ability to exercise
- enrolled in another exercise research study
- no reported trouble with memory or concentration
- non-consent of physician
Where it is running
- Freer Hall, University of Illinois — Urbana, Illinois, United States
Full record on ClinicalTrials.gov
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