Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional Outcomes

Completed · Not applicable · Has a placebo group

Conditions studied: Rotator Cuff Tear Arthropathy

In brief

This will be a randomized controlled trial to determine if postoperative ibuprofen after arthroscopic rotator cuff repair impacts postoperative opiate medication use, Visual Analog Scale (VAS) pain scores, shoulder range of motion (ROM), and repair integrity.

Key facts

Study ID

NCT02588027

Run by

University of California, San Francisco

People needed

110

Starts

2015-10-01

Expected to finish

2022-09-01

Last updated by the study team

2024-12-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients 18 years or older
• Patients that undergo arthroscopic rotator cuff repair only

You may not qualify if…

• Patients less than 18 years of age, pregnant, are incarcerated. Women who are not post-menopause are screened for pregnancy preoperatively with a urine test per our UCSF Orthopaedic Institute preoperative guidelines.
• Patients who are unable to and not willing to comply with the study protocol and follow-up visits
• Patients with a history of prior rotator cuff repair
• Patients with rotator cuff tears that require open repair
• Patients with an allergy to ibuprofen or anti-inflammatory medications
• Patients with a medical chart record or those who report a history of upper gastroenterology bleed or gastric ulcers
• Patients who are currently on warfarin, enoxaparin, heparin, or a factor Xa inhibiting anti-coagulation medication
• Patients with a known past medical history of chronic kidney disease, history of kidney transplant, or eGFR < 60 mL/min per 1.73m2.

Where it is running

• UCSF Orthopaedic Institute — San Francisco, California, United States

Full record on ClinicalTrials.gov

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