Comparative Effectiveness of Two Treatments for Veterans With PTSD

Completed · Not applicable

Conditions studied: Posttraumatic Stress Disorder

In brief

Interpersonal problems such as relationship conflict and social isolation are common among Veterans with PTSD and serve as barriers to successful posttraumatic adjustment. The main interventions for PTSD at VA facilities, i.e., Prolonged Exposure, Cognitive Processing Therapy, and Trauma-Focused CBT, do not directly target these relationship difficulties and many Veterans do not complete these treatments. Couple and family approaches for PTSD address relationship problems, but logistical problems make it difficult for couples to attend sessions and these approaches do not involve Veterans who are socially isolated or unmarried. There is accumulating evidence that Interpersonal Psychotherapy (IPT) for PTSD may be effective in reducing symptoms and improving interpersonal functioning. This study, a randomized controlled trial, aims to provide evidence regarding whether IPT for PTSD could be a useful addition to current treatments delivered at the VA.

Key facts

Study ID

NCT02586064

Run by

VA Office of Research and Development

People needed

115

Starts

2016-09-01

Expected to finish

2020-03-31

Last updated by the study team

2021-07-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Veterans age 18 or older
• Experienced trauma while deployed to a war zone
• Meet DSM-5 criteria for PTSD and a minimum CAPS-5 score of 23
• Have at least one area of relationship dysfunction
• Consent to be randomized

You may not qualify if…

• Current severe substance use disorder
• Current psychotic symptoms
• Current mania or un-medicated Bipolar Disorder
• Imminent threat of suicide or homicide
• Victim or perpetrator of severe domestic violence in the past 12 months
• Currently receiving Cognitive Behavioral Therapy for PTSD
• Psychotropic medication start or dosage change within the prior 4 weeks

Where it is running

• Southeast Louisiana Veterans Health Care System, New Orleans, LA — New Orleans, Louisiana, United States
• Providence VA Medical Center, Providence, RI — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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