Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue

Recruiting now · Not applicable

Conditions studied: Tongue Neoplasms, Tongue Cancer, Oral Cancer

In brief

This study will fill a scientific gap in the current knowledge providing data for evaluation of the palatal augmentation prosthesis (PAP) as a therapeutic modality post-surgery. This is a robust scientific randomized prospective clinical trial. Positive outcomes from this study have the potential to dramatically alter the most common issues of oral cancer therapy, namely speech and swallowing functions. Patients will have been diagnosed with a cancer lesion of the tongue requiring surgery and removal of part of the tongue. Smaller cancers of the tongue are sized as T1 or T2. For patients with smaller lesions, a PAP, which can aid in speaking and swallowing, is not routinely provided.

Key facts

Study ID

NCT02584270

Run by

University of Michigan

People needed

40

Starts

2018-01-02

Expected to finish

2028-06-01

Last updated by the study team

2026-05-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with a new diagnosis of a T1/T2 tongue cancer

You may not qualify if…

• Patients with recurrent disease
• Patients with a history of prior head and neck radiation therapy
• Patients who lack adequate maxillary dentition to support a palatal augmentation prosthesis

Where it is running

• University of Michigan Department of Oral and Maxillofacial Surgery and Hospital Dentistry — Ann Arbor, Michigan, United States (enrolling)

Full record on ClinicalTrials.gov

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