Study of Neoadjuvant Nivolumab in Patients With Non-metastatic Stage II-IV Clear Cell Renal Cell Carcinoma

Completed · Phase 1

Conditions studied: Clear Cell Renal Cell Carcinoma

In brief

This study will evaluate the use of nivolumab before surgery in patients with high-risk clear cell renal cell carcinoma who are eligible for nephrectomy. Nivolumab is an antibody that may help activate the immune system by blocking the function of an inhibitory molecule, Programmed cell death-1 (PD-1).

Key facts

Study ID
NCT02575222
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
People needed
17
Starts
2016-02-01
Expected to finish
2020-06-09
Last updated by the study team
2020-06-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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