The Effects of Sleep on Human Microbiota: Implications for Health and Disease

Recruiting now · Not applicable

Conditions studied: Sleep

In brief

The aggregate of microorganisms inhabiting the human body can be regarded as a dynamic reflector of both healthy and disease states, altering in response to changes in the environment. This may precede clinically detectable disease; and thereby, could be used to predict disease onset and additionally monitor response to treatment and predict prognosis. The primary hypothesis of this pilot study is that the human microbial communities are influenced by sleep and altered in humans with abnormal sleep patterns, and they may ultimately relate to disease risk.

Key facts

Study ID

NCT02573753

Run by

Mayo Clinic

People needed

5000

Starts

2015-10-01

Expected to finish

2031-12-01

Last updated by the study team

2026-08-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Only subjects who are eligible for ongoing IRB-approved studies will be deemed eligible for this protocol.

You may not qualify if…

• Pregnant or breast-feeding women
• Subjects who are ineligible for ongoing IRB-approved studies will not be included in this protocol

Where it is running

• Mayo Clinic Rochester — Rochester, Minnesota, United States (enrolling)

Full record on ClinicalTrials.gov

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