Physiologic Effects of RBC Transfusion

Stopped early · Phase 4

Conditions studied: Red Blood Cell Transfusion

In brief

The purpose of this study is to determine how red blood cell transfusions, particularly the length of storage time of units of packed red blood cells, affects the cardiovascular function in patients receiving transfusions. This study will also determine the most ideal way of storing and processing blood, and assess how transfusion affects a person's ability to exercise and how their blood vessels relax and contract.

Key facts

Study ID

NCT02566577

Run by

Emory University

People needed

15

Starts

2013-07-01

Expected to finish

2018-03-01

Last updated by the study team

2019-05-24

Who can join

Age: 21 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects with any condition resulting in transfusion-dependent anemia

You may not qualify if…

• Age <21 or >80 years
• Pregnancy
• Acute infection in previous 4 weeks
• Active substance abuse within the past year
• Inability to give informed consent
• Inability to return for follow-up
• The presence of alloantibodies that would limit the blood bank's ability to obtain correctly aged red blood cell (RBC) units

Where it is running

• Emory University Hospital — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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