Perfusion Imaging With Myocardial Contrast Echocardiography in HCM

Status unconfirmed · Not applicable

Conditions studied: Hypertrophic Cardiomyopathy

In brief

The objective of this study is to determine whether myocardial contrast echocardiography in patients with cardiomyopathy (HCM) can detect resting hypo-perfusion due to fibrosis or stress induced perfusion defects due to associated abnormalities in intramyocardial arteries and the microcirculation. A secondary aim will be to determine whether abnormalities in perfusion are associated with either severity of symptoms (chest pain and dyspnea), presence of arrhythmias, and regional function of the septum.

Key facts

Study ID

NCT02560467

Run by

Oregon Health and Science University

People needed

10

Starts

2015-12-01

Expected to finish

2019-09-15

Last updated by the study team

2019-06-06

Who can join

Age: 19 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-80 years
• Established diagnosis of HCM

You may not qualify if…

• Known history of coronary or peripheral artery disease
• History of myocardial infarction
• Pregnant or lactating females
• Hypersensitivity to any ultrasound contrast agent
• Evidence right-to-left or bi-directional intracardiac shunt
• Moderate or greater valve disease other than from HCM (systolic anterior motion of the mitral valve)
• History of septal ablation or myectomy
• Hemodynamic instability
• Pacemaker dependent heart rhythm

Where it is running

• Oregon Health & Science University — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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