Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-proBNP in Patients Stabilized From an Acute Heart Failure Episode.

Completed · Phase 4 · Has a placebo group

Conditions studied: Acute Heart Failure

In brief

The purpose of this study was to assess the effect of in-hospital initiation of sacubitril/valsartan (LCZ696) vs. enalapril on time averaged proportional change in NT-proBNP in patients who have been stabilized following hospitalization for acute decompensated heart failure (ADHF) and reduced ejection fraction (left ventricular ejection fraction (LVEF) ≤ 40%).

Key facts

Study ID
NCT02554890
Run by
Novartis Pharmaceuticals
People needed
887
Starts
2016-04-29
Expected to finish
2018-07-24
Last updated by the study team
2021-01-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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