Osteoclast Inhibition and Bone Formation

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Bone Loss, Aging

In brief

This protocol addresses: 1) How gene expression changes in bone cells are affected by aging? 2) Is aging associated with decreased signaling between bone cells? 3) How does treatment with the osteoporosis medication denosumab affect bone cell signaling?

Key facts

Study ID
NCT02554695
Run by
Mayo Clinic
People needed
81
Starts
2015-10-20
Expected to finish
2016-10-25
Last updated by the study team
2018-01-05

Who can join

Age: 25 and older, up to 80. Sex: female. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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