The Anti-inflammatory Effect of Prophylactic Macrolides on Children With Chronic Lung Disease

Completed · Not applicable · Has a placebo group

Conditions studied: Chronic Lung Disease

In brief

The purpose of this study is to determine if the prophylactic use of azithromycin will reduce the total number of days when unscheduled treatment is given outside of the home in a clinic, urgent care, emergency room or hospital setting between the respiratory illness season months (October 1-March 31) and subsequent 2 month follow-up (April and May)

Key facts

Study ID

NCT02544984

Run by

The University of Texas Health Science Center, Houston

People needed

60

Starts

2015-10-01

Expected to finish

2017-03-31

Last updated by the study team

2018-06-06

Who can join

Age: 1 and older, up to 6. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• children with a diagnosis of chronic lung disease (CLD) secondary to bronchopulmonary dysplasia (BPD) as defined by ATS.
• children who receive primary care at High Risk Infant Clinic or High Risk Children's Clinic

You may not qualify if…

• Children with Cystic Fibrosis or bronchiectasis
• Children with cardiac arrhythmias
• Children with cyanotic heart disease
• Children with colitis
• Children with a known Macrolide allergy
• Children taking medications known to interact with macrolides
• Children with short bowel syndrome
• Children with kidney or liver failure

Where it is running

• High Risk Children's Clinic — Houston, Texas, United States

Full record on ClinicalTrials.gov

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