SDF1 Plasmid Treatment for Patients With Peripheral Artery Disease
Status unconfirmed · Phase 2 · Has a placebo group
Conditions studied: Peripheral Arterial Disease
In brief
To investigate the efficacy of the administration of JVS-100 delivered via direct intramuscular injections on a 3 month and 6 month composite endpoint of wound progression, healing and limb loss in patients with severe peripheral arterial disease with non-healing chronic wounds who undergo an open bypass grafting or endovascular procedure for treatment of infrapopliteal disease and are dosed within 12 days and 3 months following the procedure.
Key facts
- Study ID
- NCT02544204
- Run by
- Juventas Therapeutics, Inc.
- People needed
- 120
- Starts
- 2015-11-01
- Expected to finish
- 2017-11-01
- Last updated by the study team
- 2016-11-02
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Medical College of Wisconsin — Milwauke, Wisconsin, United States (enrolling)
- UC Davis — Davis, California, United States (enrolling)
- Cedars-Sinai Heart Institute — Los Angeles, California, United States (enrolling)
- Lifespan Health System — Providence, Rhode Island, United States (enrolling)
- VCU — Richmond, Virginia, United States (enrolling)
- Morton Plant Hosptial - Baycare — Clearwater, Florida, United States (enrolling)
- Mount Sinai Medical Center — Miami, Florida, United States (enrolling)
- St. Joseph's Hospital — Tampa, Florida, United States (enrolling)
- Northwestern — Chicago, Illinois, United States (enrolling)
- RUMC — Chicago, Illinois, United States (enrolling)
- Cardiovascular Institute of the South — Houma, Louisiana, United States (enrolling)
- St. John Hospital and Medical Center — Detroit, Michigan, United States (enrolling)
- Mayo — Rochester, Minnesota, United States (enrolling)
- Cardiology Associates Research — Tupelo, Mississippi, United States (enrolling)
- St. Luke's Mid America Heart Institute — Kansas City, Missouri, United States (enrolling)
- Holy Name Medical Center — Teaneck, New Jersey, United States (enrolling)
- UNC — Chapel Hill, North Carolina, United States (enrolling)
- NC Heart and Vascular Research — Raleigh, North Carolina, United States (enrolling)
- Summa Health — Akron, Ohio, United States (enrolling)
- Cleveland Clinic — Cleveland, Ohio, United States (enrolling)
- Metro Health — Cleveland, Ohio, United States (enrolling)
- University Hospitals — Cleveland, Ohio, United States (enrolling)
- MedStar Georgetown UH — Washington D.C., District of Columbia, United States
- Cardiovascular Associates of the Southeast — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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