Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)
Recruiting now
Conditions studied: Undiagnosed Diseases, Cardiovascular Disease
In brief
Background: Studies show that rare genetic variants might lead to diseases. Researchers want to collect blood and tissue samples so they can study them and better understand diseases. Objective: To collect blood and tissue samples for studies to identify underlying causes of disease. Eligibility: People of all ages Design: Participants will have blood and/or tissue samples collected. Samples can be collected at the NIH Clinical Center. Participants doctors can collect the samples and send them to NIH. NIH staff can collect samples off site. For blood samples, blood is taken from an arm vein using a needle. Tissue collection may involve: Buccal smear: Cells are collected by scraping the inside of the cheek with a cotton swab. Saliva collection: Participants spit into a cup. Skin biopsy: A special needle takes a very small skin sample. Surgical waste tissue: If participants have surgery, NIH may receive samples of tissue that would routinely be removed. Umbilical cord or cord blood collection: If a participant has a baby, NIH may receive a small piece of the umbilical cord or blood from the cord once the baby is delivered.
Key facts
- Study ID
- NCT02543996
- Run by
- National Heart, Lung, and Blood Institute (NHLBI)
- People needed
- 10000
- Starts
- 2015-09-17
- Expected to finish
- 2050-05-22
- Last updated by the study team
- 2026-08-04
Who can join
Age: 0 and older, up to 100. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- Healthy volunteers unable to give informed consent
- Cognitively impaired individuals who are not affected
- Cognitively impaired individuals who are not related to affected subjects.
Where it is running
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States (enrolling)
Full record on ClinicalTrials.gov
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