Detecting Recurrent Prostate Cancer With 11C-choline Positron Emission Tomography

NO_LONGER_AVAILABLE

Conditions studied: Prostate Cancer, Recurrent Prostate Cancer

In brief

The purpose of this study is to use a new imaging drug called 11C-choline that is used with a PET/CT scan to see prostate cancer when it cannot be seen well on other scans, such as bone scans, CT or MRI.

Key facts

Study ID

NCT02531672

Run by

Memorial Sloan Kettering Cancer Center

Last updated by the study team

2020-06-05

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Patient must have biopsy-proven adenocarcinoma of the prostate initially treated with curative intent (surgery and radiation therapy are most common treatments but other treatments are also eligible).
• Biochemical recurrence defined as any of the following:
• PSA ≥ 0.2 ng/mL in at least two sequential tests for patients treated with surgery.
• PSA ≥ 0.2 ng/mL above the post therapy nadir for patients treated with radiation therapy, brachytherapy or cryotherapy.
• PSA ≥ 0.2 ng/ml above the most recent therapy nadir for patients who have received additional treatment in the recurrent setting
• Patient must have undergone standard-of-care restaging that does not clearly identify site(s) of active disease, or such prior studies must show equivocal findings for which further work-up is considered necessary to make clinical decision. Standard staging examinations may include one or more of the following: CT or MRI, bone imaging (either Tc-99m bisphosphonate scintigraphy MDP or F-18 sodium fluoride PET), FDG PET, or In-111 capromab pendetide scintigraphy no older than 3 months of consent date.
• Age ≥ 18 years.
• Patient must be able to tolerate PET/CT imaging.
• Patient must be able to understand and willing to sign a written informed consent document.

You may not qualify if…

• Patient must not have claustrophobia that would preclude PET/CT imaging or other contraindications to CT imaging.

Where it is running

• Memoral Sloan Kettering Basking Ridge (Consent Only) — Basking Ridge, New Jersey, United States
• Memorial Sloan Kettering Bergen (Consent only ) — Montvale, New Jersey, United States
• Memorial Sloan Kettering Cancer Center @ Commack (Consent Only) — Commack, New York, United States
• Memoral Sloan Kettering Westchester (Consent only) — Harrison, New York, United States
• Memorial Sloan Kettering Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

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