Pilot Study to Assess the Quantitative Dermal Transfer Efficiencies of Solids for Multiple Transfer Pathways
Completed · Not applicable
Conditions studied: Environmental Exposure
In brief
Dermal transfer efficiency has been defined as the amount of material that moves from one surface to another following contact. The investigators propose to measure dermal transfer efficiency for the following pathways: (1) object to skin, (2) skin to skin, (3) skin to mouth, (4) clothing to skin, (5) gloves to skin, and (6) air to skin. First, the quantitative dermal transfer will be measured for the two selected test substances (lead, Tinopal) for each of these six pathways. The relative quantities of dermal transfer will also then be compared between the different transfer pathways (e.g., is skin to skin transfer greater or less than clothing to skin transfer?). And second, the pattern of transfer will be characterized semi-quantitatively (e.g., does dermal transfer occur consistently and evenly to the skin from different reservoirs?).
Key facts
- Study ID
- NCT02529748
- Run by
- University of Minnesota
- People needed
- 10
- Starts
- 2015-08-01
- Expected to finish
- 2019-07-31
- Last updated by the study team
- 2019-08-15
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Adult volunteers with healthy intact skin.
You may not qualify if…
- Children will be excluded from the study.
- Adults with a past history of dermal sensitization, skin allergy, or dermal irritation or dermatitis because of the potential to have compromised barrier function in the skin.
- Adults who are unwilling to follow protocol requirements.
- Adults who have a documented history of lead poisoning.
- Adults who have a concurrent contagious illness or other stressor which in the opinion of the investigator may interfere with the subject's ability to perform the study's requirements.
- Adults who have open wounds or otherwise compromised skin integrity on their hands.
- Adults who are pregnant or nursing.
- Adults who lack the capacity to provide informed voluntary consent to participate in the study.
Where it is running
- University of Minnesota — Minneapolis, Minnesota, United States
Full record on ClinicalTrials.gov
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