Omega-3 Supplementation for Smell Dysfunction

Completed · Not applicable

Conditions studied: Sellar/Parasellar Tumor, Smell Dysfunction

In brief

Omega-3 supplementation has been shown to have neuroprotective and potentially anti-inflammatory properties in both central and peripheral nerve injuries. The investigators are studying to see if omega-3 supplementation will affect olfactory (smell) function in patients with olfactory dysfunction following endoscopic removal of pituitary tumors.

Key facts

Study ID

NCT02529332

Run by

Stanford University

People needed

110

Starts

2014-09-01

Expected to finish

2018-04-01

Last updated by the study team

2018-08-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• sellar/parasellar tumor scheduled to undergo endoscopic transnasal transsphenoidal resection
• 18 years of age or older
• English speaking

You may not qualify if…

• Currently using blood thinning agents (aside from NSAIDs or cardioprotective ASA)
• elevated AST, ALT, or alk phos >10% outside of normal range, if randomized to omega-3 group
• diabetes, if randomized to omega-3 group and not already on omega-3 prescribed by another provider
• unable to provide informed consent due cognitive deficiencies

Where it is running

• Stanford University — Stanford, California, United States
• Emory University Hospital — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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