Heart Rate Variability in Depression
Completed · Not applicable
Conditions studied: Major Depressive Disorder
In brief
The purpose of this study is to understand if there is a relationship between the way that emotions are regulated by the brain and the way that heart rate is regulated by the brain. The study also seeks to understand whether having depression changes the way that emotions and heart rate are regulated.
Key facts
- Study ID
- NCT02525978
- Run by
- Emory University
- People needed
- 8
- Starts
- 2015-07-01
- Expected to finish
- 2017-04-12
- Last updated by the study team
- 2019-09-20
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Ages 18-65 years
- Able to understand and provide informed consent
- Male and female
- Depressed Subjects:
- Current diagnosis of major depressive disorder (MDD) and currently in an major depressive episode (MDE)
- Quick Inventory of Depressive Symptomology (QIDS-SR16) score of 11 or greater
- Anticipated treatment with ketamine infusion for depression
You may not qualify if…
- Current daily use of tricyclic antidepressants
- Current diagnosis of cardiac arrhythmia or heart failure
- Pregnancy
- Current use of cardiac medications of the class beta-blockers
- Current treatment with deep brain stimulation for any reason
- Healthy Controls:
- Current psychiatric treatment, including use of antidepressants or daily use of anxiolytic medication
- Depressed Subjects:
- Previous history of ketamine infusion for depression
- Psychotic symptoms
- Active co-morbid psychiatric diagnosis including anxiety disorder or personality disorder that significantly affects the current clinical condition, as determined by medical records
Where it is running
- Emory University Hospital — Atlanta, Georgia, United States
- 12 Executive Park Drive — Atlanta, Georgia, United States
- Emory University at Wesley Woods Hospital — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
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