Wine Consumption and Glycemic Control

Completed · Not applicable

Conditions studied: Diabetes Mellitus, Type 2

In brief

Many studies have reported that alcoholic beverage consumption, especially in the form of wine, reduces the risk of developing type 2 diabetes by as much as 40%. This association suggests that wine consumption may somehow improve the body's ability to control its blood glucose concentration. Indeed, it has been reported that when wine is consumed immediately prior to ingestion of glucose, the release of insulin is enhanced and blood glucose concentration is lowered. The mechanism of wine's effects on blood glucose concentration is unknown, but is likely related to its ethanol or antioxidant content. In this study, the investigators plan to test whether wine or plain ethanol (vodka) ingestion alters the control of blood glucose in subjects who have diabetes or pre-diabetes.

Key facts

Study ID

NCT02518334

Run by

University of Missouri-Columbia

People needed

14

Starts

2012-03-01

Expected to finish

2015-03-01

Last updated by the study team

2017-10-26

Who can join

Age: 21 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• insulin resistant: diagnosed with pre-diabetes or fasting blood glucose >/= 97 mg/dL
• T2D: diagnosed by primary care physician
• at risk of type 2 diabetes (obesity and physically inactive)
• age: 21-65

You may not qualify if…

• smoking
• insulin use (other than once daily)
• physically active (>30 mins aerobic exercise two days/week)
• recent (>3 mo) changes in medication use or dose
• uncontrolled type two diabetes (HbA1C >10%)
• advanced retinopathy or neuropathy
• pregnancy

Where it is running

• University of Missouri — Columbia, Missouri, United States

Full record on ClinicalTrials.gov

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