Effects of Abatacept in Patients With Early Rheumatoid Arthritis

Completed · Phase 3 · Has a placebo group

Conditions studied: Rheumatoid Arthritis

In brief

The purpose of this study is to determine if abatacept is effective in the treatment of early rheumatoid arthritis.

Key facts

Study ID

NCT02504268

Run by

Bristol-Myers Squibb

People needed

994

Starts

2015-09-03

Expected to finish

2020-03-19

Last updated by the study team

2021-06-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Rheumatoid arthritis (RA) diagnosis less than 6 months
• CRP > 3 mg/L or Erythrocyte Sedimentation Rate (ESR) ≥ 28 mm/h
• At least 3 swollen and 3 tender joints
• Anti-citrullinated protein antibodies (ACPA) positive

You may not qualify if…

• At risk for tuberculosis
• Have acute infection
• Have chronic or recurrent bacterial or serious latent viral infection
• History of malignancies in the last 5 years except squamous skin, basal skin or cervical carcinoma
• Previous treatment with any conventional or biologic Disease-modifying anti rheumatic drugs (DMARD)

Where it is running

• Arizona Arthritis & Rheumatology Research PLLC — Glendale, Arizona, United States
• Arizona Arthritis & Rheumatology Research PLLC — Mesa, Arizona, United States
• Arizona Arthritis & Rheumatology Research PLLC — Phoenix, Arizona, United States
• Arizona Arthritis & Rheumatology Research PLLC — Phoenix, Arizona, United States
• Arizona Arthritis & Rheumatology Research PLLC — Sun City, Arizona, United States
• CHI St. Vincent Medical Group Hot Springs — Hot Springs, Arkansas, United States
• Arkansas Primary Care Clinic — Little Rock, Arkansas, United States
• St. Joseph Heritage Medical Group — Fullerton, California, United States
• Healthcare Partners Medical Group — Huntington Beach, California, United States
• Valerius Medical Group and Research Center — Los Alamitos, California, United States
• Inland Rheumatology Clinical Trials Inc. — Upland, California, United States
• Joao Nascimento — Bridgeport, Connecticut, United States
• Rheumatology Associates Of Central Florida, P.A. — Orlando, Florida, United States
• Tampa Medical Group, Pa — Tampa, Florida, United States
• Coeur D'Alene Arthrit Clin — Coeur d'Alene, Idaho, United States
• Arthritis And Diabetes Clinic — Monroe, Louisiana, United States
• Klein And Associates, M.D., Pa — Hagerstown, Maryland, United States
• St. Paul Rheumatology, P.A. — Eagan, Minnesota, United States
• Arthritis Consultants — St Louis, Missouri, United States
• Physician Research Collaboration, Llc — Lincoln, Nebraska, United States
• Arthritis And Osteoporosis Associates, Pa — Freehold, New Jersey, United States
• Physicians Research Center, Llc — Toms River, New Jersey, United States
• Albuquerque Center For Rheumatology — Albuquerque, New Mexico, United States
• Albuquerque Clinical Trials — Albuquerque, New Mexico, United States
• Rheumatology Associates Of North Alabama, P.C. — Huntsville, Alabama, United States

Full record on ClinicalTrials.gov

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