Clinical Registry Assessment of the Missouri Osteochondral Allograft Preservation System - MOPS

Enrolling by invitation

Conditions studied: Symptomatic Osteochondral Defect(s), Cartilage, Meniscus, Ankle, Knee, Shoulder, Hip

In brief

With institutional review board approval and informed consent, patients are prospectively enrolled into a registry to follow outcomes after osteochondral allograft (OCA) and/or meniscal allograft transplantation. Patients are included when 1 year followup data are available, including complications and reoperations, patient reported outcome measures (PROMs), compliance with rehabilitation, revisions, and failures. In addition, MOPS grafts are compared to standard preservation grafts, and unipolar, multisurface, and bipolar cohorts, as well as patient compliance variables, are compared.

Key facts

Study ID

NCT02503228

Run by

University of Missouri-Columbia

People needed

5000

Starts

2015-06-01

Expected to finish

2050-12-01

Last updated by the study team

2026-07-30

Who can join

Age: 13 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults and children age ≥13 years
• Knee, hip, ankle, or shoulder osteochondral defect ≥15mm as determined by MRI or diagnostic knee arthroscopy for allograft transplantation
• Must be physically and mentally willing and able to comply with postoperative and routinely scheduled clinical and radiographic evaluations.
• Must be able to read and understand English or a language for which translated versions of the patient reported questionnaires and Informed consent form are available.
• Must be able to sign informed consent and must voluntarily sign the Institutional Review Board (IRB)/Independent Ethics Committee (IEC)-approved subject Informed Consent Form.

You may not qualify if…

• Is a prisoner
• Is receiving workman's compensation
• Subject is mentally incompetent such that would preclude the subject from providing adequate consent and/or complying with study requirements

Where it is running

• University of Missouri — Columbia, Missouri, United States

Full record on ClinicalTrials.gov

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