Musculoskeletal Ultrasound in Asymptomatic Hyperuricemia

Status unconfirmed

Conditions studied: Hyperuricemia

In brief

An observational study to evaluate the prevalence of US changes of gout in the joints and tendons of patients with different degrees of asymptomatic hyperuricemia. The investigators' findings may support the extension of the spectrum of urate disease, and define a subset of patients that may benefit from early urate-lowering therapy.

Key facts

Study ID

NCT02502565

Run by

Washington D.C. Veterans Affairs Medical Center

People needed

150

Starts

2012-01-01

Expected to finish

2019-03-01

Last updated by the study team

2018-06-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients must have at least one serum uric acid level l ≥ 7.0 mg/dL within the last two years without a clinical diagnosis of gout per American College of Rheumatology criteria30 (appendix A).
• Patients, of matched gender and age, with normal uric acid levels will serve as controls.

You may not qualify if…

• Patients who meet or have met the ACR criteria for Gout, unable to read English, and/or have terminal illness will not be eligible to participate in the study.
• Patients with a diagnosis of skin psoriasis31, rheumatoid arthritis, or spondyloarthropathies will not be eligible to participate.
• Patients who are on urate-lowering therapy.
• Patients with 1 or 2 total knee replacements.

Where it is running

• Howard University Hospital — Washington D.C., District of Columbia, United States
• WashingtonVAMC — Washington D.C., District of Columbia, United States

Full record on ClinicalTrials.gov

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