Mechanisms of Mindfulness Training and Stress Reduction

Completed · Not applicable

Conditions studied: Psychological Stress, Mindfulness

In brief

This study is a three-arm randomized controlled trial of a mindfulness stress reduction intervention, with the aim of dismantling the experience-monitoring and nonjudgmental-acceptance elements of mindfulness programs to determine the active treatment component. In addition to enhancing understanding of mechanisms underlying the effects of mindfulness interventions, identifying the therapeutic constituent(s) could inform development of targeted interventions as well as provide strategies to optimize adherence.

Key facts

Study ID

NCT02502227

Run by

Carnegie Mellon University

People needed

137

Starts

2015-07-01

Expected to finish

2017-01-01

Last updated by the study team

2017-02-01

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• English speaking
• Moderate- to high-stress
• Owns an internet-enabled smart phone

You may not qualify if…

• Diagnosis of chronic mental (e.g. recurrent depression, schizophrenia, personality disorder) or physical disease (e.g. cancer, HIV, diabetes)
• Hospitalization in past 3 months
• Medication use that interferes with cortisol activity (e.g. corticosteroids)
• Current oral contraceptive use
• Pregnancy
• Current antibiotic, antiviral, or antimicrobial treatment
• Travel outside the country within the past 6 months to any country on the Center for Disease Control travel alert list
• Recreational drug use, excessive alcohol or tobacco use
• Significant experience with or daily practice of mindfulness meditation or related mind-body practice

Where it is running

• Carnegie Mellon University — Pittsburgh, Pennsylvania, United States
• University of Pittsburgh Medical Center- Center for Integrative Medicine — Pittsburgh, Pennsylvania, United States
• Pennsylvania State University — University Park, Pennsylvania, United States

Full record on ClinicalTrials.gov

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