Real-time fMRI and Neurofeedback of Brain Networks Mediating Trauma Memory Recall in PTSD
Completed · Not applicable
Conditions studied: Stress Disorders, Post-Traumatic
In brief
The purpose of the current study is to develop a better understanding of the brain mechanisms involved in psychological treatments for posttraumatic stress disorder (PTSD). This project will build on past research using script-driven imagery in our lab by investigating brain activity in areas activated during exposure to trauma-related cues. This project will also develop new knowledge concerning volitional control of those areas. The ultimate goal of this study is a better understanding of whether volitional control of these brain areas will improve therapeutic outcomes. This process will first be piloted in a sample of healthy controls. This will allow investigators to refine the methodology prior to recruiting a sample with PTSD.
Key facts
- Study ID
- NCT02500719
- Run by
- University of Arkansas
- People needed
- 30
- Starts
- 2015-08-15
- Expected to finish
- 2019-04-01
- Last updated by the study team
- 2021-08-20
Who can join
Age: 21 and older, up to 50. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Female
- Aged 21-50
- Medically healthy
You may not qualify if…
- Claustrophobia, or the inability to lie still in a confined space
- Major medical disorders (e.g., HIV, cancer)
- Magnetic metallic implants (such as screws, pins, shrapnel remnants, aneurysm clips, artificial heart valves, inner ear (cochlear) implants, artificial joints, and vascular stents)
- Electronic or magnetic implants, such as pacemakers
- Permanent makeup or tattoos with metallic dyes
- Currently pregnant
- A self-reported history of loss of consciousness (greater than 10 minutes)
- Physical disabilities that prohibit task performance (such as blindness or deafness)
- Psychotic disorders (e.g., schizophrenia)
- Any other condition that the investigator believes might put the participant at risk
Where it is running
- University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
Full record on ClinicalTrials.gov
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