Study to Assess MEDI4736 With Either AZD9150 or AZD5069 in Advanced Solid Tumors & Relapsed Metastatic Squamous Cell Carcinoma of Head & Neck

Completed · Phase 1/Phase 2

Conditions studied: Advanced Solid Tumors & Metastatic Squamous Cell Carcinoma of the Head and Neck

In brief

This multicentre, open-label, Phase 1b/2 study is designed as a 2 part study consisting of a dose-escalation, safety run-in Part A and a dose-expansion Part B

Key facts

Study ID

NCT02499328

Run by

AstraZeneca

People needed

340

Starts

2015-08-06

Expected to finish

2025-10-08

Last updated by the study team

2026-02-11

Who can join

Age: 18 and older, up to 130. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Research Site — Birmingham, Alabama, United States
• Research Site — Duarte, California, United States
• Research Site — La Jolla, California, United States
• Research Site — Los Angeles, California, United States
• Research Site — Los Angeles, California, United States
• Research Site — Orange, California, United States
• Research Site — San Francisco, California, United States
• Research Site — Denver, Colorado, United States
• Research Site — Plantation, Florida, United States
• Research Site — Sarasota, Florida, United States
• Research Site — Lafayette, Indiana, United States
• Research Site — Boston, Massachusetts, United States
• Research Site — Detroit, Michigan, United States
• Research Site — Billings, Montana, United States
• Research Site — Morristown, New Jersey, United States
• Research Site — Cincinnati, Ohio, United States
• Research Site — Houston, Texas, United States
• Research Site — Fairfax, Virginia, United States
• Research Site — Seattle, Washington, United States
• Research Site — Antwerp, Belgium
• Research Site — Brussels, Belgium
• Research Site — Brussels, Belgium
• Research Site — Edegem, Belgium
• Research Site — Namur, Belgium
• Research Site — Berlin, Germany

Full record on ClinicalTrials.gov

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