Establishing of Neuronal-like Cells From Patients With Cisplatin-Induced Peripheral Neuropathy
Withdrawn before enrolling
Conditions studied: Peripheral Nervous System Diseases, Testicular Neoplasms
In brief
This study targets patients with cisplatin-induced peripheral neuropathy and will allow us to: a) study peripheral neuropathy in diverse human sensory neurons in ways that were not possible previously; b) gain insight on druggable targets to treat or prevent this devastating side effect of chemotherapy; c) provide a human cellular model that can be used for screening of drugs to determine if they are neurotoxic. The combination of patient information and in vitro measurements provides a highly relevant and clinically useful model for studies aimed to impact treatment selection for the individual cancer patient.
Key facts
- Study ID
- NCT02492360
- Run by
- Costantine Albany
- People needed
- 0
- Starts
- 2017-12-01
- Expected to finish
- 2019-12-01
- Last updated by the study team
- 2018-02-28
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
Where it is running
- IU Simon Cancer Center — Indianapolis, Indiana, United States
Full record on ClinicalTrials.gov
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