Comparison of CHS-1420 Versus Humira in Subjects With Chronic Plaque Psoriasis

Completed · Phase 3

Conditions studied: Plaque Psoriasis

In brief

This is a 3-period study comparing CHS-1420 to Humira in patients with chronic plaque psoriasis.

Key facts

Study ID

NCT02489227

Run by

Coherus Oncology, Inc.

People needed

545

Starts

2015-08-01

Expected to finish

2017-03-01

Last updated by the study team

2020-04-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female adults
• PsO diagnosis for 6 months
• Active disease: PASI greater than or equal to 12, Physician's Static Global Assessment (PSGA) score greater than or equal to 3 (based on a scale of 0-5),
• Body Surface Area (BSA) involved with PsO greater than or equal to 10%

You may not qualify if…

• Forms of psoriasis other than PsO
• Drug induced psoriasis
• Positive QuantiFERON-tuberculosis (TB) Gold Test
• Presence of significant comorbid conditions
• Chemistry and hematology values outside protocol specified range
• Major systemic infections

Where it is running

• Encino Research Center — Encino, California, United States
• Center for Dermatology and Laser Surgery — Sacramento, California, United States
• Kenneth M Stein, MD — Santa Rosa, California, United States
• HealthCare Partners Medical Group Clinical Research Center — Torrance, California, United States
• Horizons Clinical Research Center, LLC. — Denver, Colorado, United States
• New England Research Associates LLC — Trumbull, Connecticut, United States
• Francisco A Kerdel, MD — Coral Gables, Florida, United States
• Linda Tripodis Murray, DO — Pinellas Park, Florida, United States
• ACRC-Dermatology — West Palm Beach, Florida, United States
• Mark A Knautz, MD — Marietta, Georgia, United States
• The Indiana Clinical Trials Center — Plainfield, Indiana, United States
• Grekin Skin Institute — Warren, Michigan, United States
• Jack C Scott, MD — Edina, Minnesota, United States
• Central Dermatology — St Louis, Missouri, United States
• Craig L Leonardi, MD — St Louis, Missouri, United States
• PMG Research of Raleigh, LLC — Cary, North Carolina, United States
• Box Arthritis & Rheumetology of the Carolinas — Charlotte, North Carolina, United States
• Michael Joseph Noss, MD — Cincinnati, Ohio, United States
• Central Sooner Research — Norman, Oklahoma, United States
• Health Research of Oklahoma — Oklahoma City, Oklahoma, United States
• Dermatology and Skin Surgery Center, PC — Exton, Pennsylvania, United States
• James Henry Kopp, MD — Anderson, South Carolina, United States
• PMG Research of Bristol, LLC — Bristol, Tennessee, United States
• Arlington Research Center, Inc. — Arlington, Texas, United States
• Sadra Sasha Jazayeri, MD — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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