The Effect of Bikram Yoga on Arterial Stiffness and Endothelial Function in Middle-Aged Adults
Completed · Not applicable
Conditions studied: Aging
In brief
Arterial stiffening and endothelial dysfunction are correlates of advancing age contributing to the decline in cardioprotection with age. Arterial stiffness and endothelial dysfunction are emerging risk factors for cardiovascular disease and predict future cardiac events. Vascular function has long been a target for lifestyle interventions with several studies showing improvements traditional exercise modes. However, the impact of yoga on vascular function remains elusive. This study will determine the effect of a 12-week Bikram yoga intervention on arterial stiffness and endothelial function in healthy, middle-aged adults. The overall aim of this study is to determine the efficacy of Bikram yoga in improving vascular endothelial function and arterial distensibility in middle-aged adults with risk factors for coronary artery disease and to determine whether the heated environment plays a role in mediating these alterations in vascular function. The investigators propose to conduct a 12-week Bikram yoga intervention study in sedentary individuals in order to test the following hypotheses: 1. Bikram yoga will elicit reductions in arterial stiffness and enhancements in endothelial function in sedentary, middle-aged adults. 2. The postulated effects of Bikram yoga will be greater when practiced in a heated environment.
Key facts
- Study ID
- NCT02488148
- Run by
- University of Texas at Austin
- People needed
- 81
- Starts
- 2013-09-01
- Expected to finish
- 2016-12-30
- Last updated by the study team
- 2018-10-12
Who can join
Age: 40 and older, up to 60. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- A total of 80 sedentary (<2 days of physical activity weekly) male and female adults between the ages of 40 and 60 years will be recruited and studied.
You may not qualify if…
- pregnancy (if the subject is unsure about her status, a simple testing kit will be made available to the subject)
- Uncontrolled hypertension (blood pressure >160/100 mmHg while on hypertensive medications)
- Infection within the previous 4 weeks
- Having adrenal or endocrine tumors
- Renal disease
- Prior myocardial infarction (heart attack)
- Known coronary artery disease
- Personal history of stroke
- Heart failure
- Cardiac arrhythmias
- Chronic obstructive pulmonary disease
- Personal history of psychosis
- Diabetes
- Having a body mass index ≥35 kg/m2
- Recent chest pain or dyspnea
- Orthopedic limitations that prevent them from being able to perform the yoga postures
- Heat intolerance
- Having undergone a barium test within the previous two weeks
- Having had a nuclear medicine scan or injection with x-ray dye within the previous week.
Where it is running
- Cardiovascular Aging Research Laboratory — Austin, Texas, United States
Full record on ClinicalTrials.gov
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