Pentoxifylline Treatment in Acute Pancreatitis (AP)

Completed · Phase 3 · Has a placebo group

Conditions studied: Acute Pancreatitis (AP), Gallstone Pancreatitis, Alcoholic Pancreatitis, Trauma Acute Pancreatitis, Hypertriglyceridemia Acute Pancreatitis, Idiopathic (Unknown) Acute Pancreatitis, Medication Induced Acute Pancreatitis, Cancer Acute Pancreatitis, Miscellaneous (i.e. Acute on Chronic Pancreatitis)

In brief

The purpose of this study was to determine the effects (good and bad) of giving a drug called pentoxifylline to patients with acute pancreatitis.

Key facts

Study ID

NCT02487225

Run by

Mayo Clinic

People needed

83

Starts

2015-05-01

Expected to finish

2017-10-31

Last updated by the study team

2019-01-23

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Enrollment within 72 hours of diagnosis of acute pancreatitis (AP)
• Ability to give informed consent or a Legal Adult Representative (LAR) able to give informed consent for subject when needed as defined buy LAR use guidelines.
• Adult subjects of age ≥18 years.

You may not qualify if…

• Moderate or severe congestive heart failure
• History of seizure disorders or demyelinating disease
• Nursing mothers
• Pregnancy
• History of prior tuberculosis or risk factors for tuberculosis
• Evidence of non- corticosteroid immunosuppression (such as malignancy, chronic renal failure, chemotherapy within 60 days, and HIV)
• Evidence of active hemorrhage
• Paralytic ileus with severe nausea and vomiting

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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