Brain Activation and Satiety in Children: Functional Magnetic Resonance Imaging

Completed · Not applicable

Conditions studied: Childhood Obesity

In brief

BASIC fMRI is a prospective single center intervention trial using fMRI imaging in 9-11 year old obese male and females pre and post family-based behavioral treatment of 24 weeks duration to determine the relationship between impulsivity and central satiety responses.

Key facts

Study ID

NCT02484976

Run by

Seattle Children's Hospital

People needed

81

Starts

2014-09-01

Expected to finish

2018-08-01

Last updated by the study team

2018-09-06

Who can join

Age: 9 and older, up to 11. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 9-11 years of age
• Male or female
• Ability and willingness to participate in study visits including fMRI scans and blood draws;
• ability to provide informed written consent and assent;
• BMI z-score for lean control children 15th to 84.9th perc. for age and sex,
• BMI z-score for obese children BMI z-score >90th perc. for age and sex;
• Additional inclusion criteria for obese children: One overweight parent (BMI >25 kg/m2); willingness of 1 parent (does not have to be the obese parent) to engage in family-based weight control treatment.

You may not qualify if…

• History of acute or chronic serious medical conditions;
• known diabetes mellitus or recent (6 mo.) history of anemia;
• presence of any implanted metal or metal devices, including ferro-metallic surgical clips or braces;
• claustrophobia;
• documented cognitive disorder, disruptive behavior, inability to participate in group sessions;
• current use of medications known to alter appetite, body weight, or brain response (e.g. anti-seizure medications, glucocorticoids, medications for attention deficit disorder);
• food intolerance or vegetarianism.

Where it is running

• Seattle Childrens Hospital — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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