Acute Partner and Social Contact Referral: iKnow

Completed · Not applicable

Conditions studied: Acute HIV Infection, HIV Seropositive, Sexually Transmitted Infections

In brief

The primary purpose of this research is to assess the benefit of an "unaware intervention package" for identifying high risk persons who are unaware of their HIV infection status. This intervention package includes screening for acute HIV infection, contract sexual partner referral, and peer referral.

Key facts

Study ID

NCT02467439

Run by

University of North Carolina, Chapel Hill

People needed

15310

Starts

2015-06-01

Expected to finish

2019-05-02

Last updated by the study team

2019-11-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Active and Base Case Index Participants:
• Acute HIV-1 infection documented by a negative or discordant rapid HIV test results and detectable HIV RNA OR established HIV infection based on two positive HIV antibody rapid tests at the time of screening.
• Men and women age >/= 18 years.
• Current resident in the Lilongwe area.
• Ability and willingness of participant to provide informed consent.
• Willingness to provide contact/locator information to be contacted for AHI results if rapid test is negative or discordant.
• Partners and Social Contacts (referred by active arm):
• Referred by active arm participant and presenting to STI clinics with a referral card.
• Men and women age >/= 18 years.
• Intention to remain in the Lilongwe area for the duration of the study.
• Ability and willingness of participant to provide informed consent.
• Willingness to provide contact/locator information to be contacted for AHI results if rapid test is negative or discordant.
• Partners (referred by base case arm):
• Referred by base case arm participant and presenting to STI clinics with a referral card.
• Men and women age >/= 18 years.
• Ability and willingness of participant to provide informed consent.

You may not qualify if…

• Active and Base Case Index Participants:
• HIV-negative based on one or more antibody rapid test and an HIV RNA PCR test.
• Serious illness, including tuberculosis or opportunistic infection, requiring systemic treatment and/or hospitalization.
• Active drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements.
• Any other condition that in the opinion of the study investigator would compromise the safety of the study participant or study staff, or would prevent proper conduct of the study.
• Partner and Social Contacts (referred by active or base case arm):
• Active drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements.
• Serious illness, including tuberculosis or opportunistic infection, requiring systemic treatment and/or hospitalization.
• Any other condition that in the opinion of the study investigator would compromise the safety of the study participant or study staff, or would prevent proper conduct of the study.

Where it is running

• University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.