Correlation Analysis Between Brain Lesions and Sensorimotor Impairments in Individuals With Stroke (Preliminary Study)
Completed
Conditions studied: Stroke
In brief
The objective of the preliminary study is: 1. To identify correlations between brain lesions and sensorimotor impairments in stroke. 2. To identify possible patterns between brain lesions and sensorimotor impairments that might increase our understanding in stroke recovery and guide further tailor-based neuro-rehabilitation
Key facts
- Study ID
- NCT02465281
- Run by
- University of Minnesota
- People needed
- 16
- Starts
- 2015-10-01
- Expected to finish
- 2016-09-23
- Last updated by the study team
- 2020-03-11
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Inclusion criteria for healthy subjects are:
- medically stable;
- 18 - 99 years of age;
- able to hear the instructions given during the study
- Inclusion criteria for stroke patients are:
- at least 6 months post-stroke;
- medically stable;
- 18 - 99 years of age;
- subcortical or cortical infarct confirmed with MRI;
- Mini-mental State Exam > 24/30 (Folstein et al., 1975);
- able to hear the instructions given during the study;
- able to comprehend the instructions given during the study;
- able to commit time to participate in a 6-12-weeks rehabilitation program
You may not qualify if…
- Exclusion criteria for healthy subjects are:
- having ever experienced a stroke or another brain injury or illness related to the brain that has lasting effects or effects experienced at the moment of recruitment;
- severe sensory impairments such that different movements of the finger, hand or wrist are not reliably felt;
- contractures in tested arm that hinder persons from keeping the outstretched arm in a relaxed position;
- interfering comorbidities (e.g. fracture, cancer, peripheral neuropathy);
- exhibit contra-indications to enter the magnetic field of the 3T (pacemakers, metal parts in the body etc);
- pregnant or nursing mother;
- adults lacking capacity to consent
- Exclusion criteria for stroke patients are:
- insular or cerebellar infarcts/brain lesions;
- unilateral spatial neglect, identified by a standard neuropsychological assessment (Bell's test (score/35, Gauthier et al., 1989);
- aphasia;
- apraxia (TULIA, Vanbellingen et al., 2011);
- severe sensory impairments such that different movements of the finger, hand or wrist are not reliably felt;
- contractures in the hemiplegic arm that hinder patients from keeping the outstretched arm in a relaxed position;
- interfering comorbidities (e.g. fracture, cancer, peripheral neuropathy);
- patients currently receiving therapy for their hemiplegic arm, the latter in order to avoid confounding treatment effects;
- exhibit contra-indications to enter the magnetic field of the 3T (pacemakers, metal parts in the body etc);
- pregnant or nursing mother;
- adults lacking capacity to consent
Where it is running
- University of Minnesota Medical Center — Minneapolis, Minnesota, United States
Full record on ClinicalTrials.gov
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