Systemic Steroids for Peripheral Nerve Blocks

Completed · Phase 4 · Has a placebo group

Conditions studied: Osteoarthritis, Hip

In brief

This study will investigate the ability of systemic dexamethasone to prolong the sensory block duration for lumbar plexus nerve blockade.

Key facts

Study ID

NCT02464176

Run by

Wake Forest University Health Sciences

People needed

115

Starts

2015-06-01

Expected to finish

2017-01-01

Last updated by the study team

2018-08-31

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• contraindications to regional anesthesia including, allergy to amide local anesthetics, presence of peripheral neurologic dysfunction, pre-existing coagulopathy or infection in the area of interest will be excluded.
• insulin and non-insulin dependent diabetes mellitus
• preoperative use of systemic corticosteroids within 30 days of surgery
• chronic opioid use (defined as daily opioid dose of greater than 40 mg of oxycodone equivalents or any long-acting opioid)
• pregnancy
• failure to effectively place the lumbar plexus block.
• known prior adverse reaction to dexamethasone (for example: psychosis) or an allergy to dexamethasone

Where it is running

• Wake Forest University Baptist Medical Center — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

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