Perineural Steroids for Peripheral Nerve Blocks

Completed · Phase 4 · Has a placebo group

Conditions studied: Osteoarthritis, Knee

In brief

This study will look at the efficacy of dexamethasone for prolongation of peripheral nerve blocks.

Key facts

Study ID

NCT02462148

Run by

Wake Forest University Health Sciences

People needed

85

Starts

2015-07-01

Expected to finish

2017-08-31

Last updated by the study team

2018-09-24

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• elective robotic medial MAKO partial knee arthroplasty
• agreed to a regional anesthesia technique

You may not qualify if…

• contraindications to regional anesthesia
• presence of a progressive neurological deficit
• a pre-existing coagulopathy, infection
• insulin and non-insulin dependent diabetes mellitus
• systemic use of corticosteroids within 30 days of surgery
• chronic use of an opioid analgesic (>3 months or a combined total of more than 40 mg Oxycodone equivalents a day)
• pregnancy
• a prior history of an adverse event (for example: psychosis) or an allergy to dexamethasone

Where it is running

• Wake Forest University Baptist Medical Center — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

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