Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac Arrest

Completed · Not applicable

Conditions studied: Heart Arrest, Seizures

In brief

Non-convulsive seizures (NCS) following cardiac arrest are common and are associated with worse neurologic outcomes and increased mortality. More prolonged seizures (status epilepticus) are associated with worse outcomes. Earlier diagnosis and treatment of seizures may lead to earlier termination of seizures and decreased seizure burden. This study will evaluate whether bedside intensive care unit (ICU) provider interpretation of a type of EEG called DSA EEG can be used by non-neurologists to diagnosis seizures more rapidly than continuous EEG's routinely read by neurologists.

Key facts

Study ID

NCT02458820

Run by

Children's Hospital of Philadelphia

People needed

18

Starts

2015-06-01

Expected to finish

2019-01-01

Last updated by the study team

2019-07-09

Who can join

Age: 0 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects age > 48 hours
• Return of Spontaneous Circulation (ROSC) for > 20 minutes after a cardiac arrest
• Treated in the PICU
• Clinical team ordering continuous EEG monitoring

You may not qualify if…

• Age < 48 hours old and < 38 weeks gestational age
• No available computers with DSA software

Where it is running

• Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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